崔業(yè)波; 包海鷹; 李玉
吉林農(nóng)業(yè)大學(xué)中藥材學(xué)院; 吉林農(nóng)業(yè)大學(xué)中藥材學(xué)院; 吉林農(nóng)業(yè)大學(xué)中藥材學(xué)院 長(zhǎng)春130118; 長(zhǎng)春130118; 長(zhǎng)春130118

【中文摘要】 建立靈苓神顆粒劑的制備工藝和質(zhì)量控制方法,并通過藥理實(shí)驗(yàn)研究其鎮(zhèn)靜安神的藥理作用。靈芝和茯神配伍,采用擠出制粒法制得靈苓神顆粒。通過小鼠的催眠實(shí)驗(yàn)和影響小鼠自主活動(dòng)的藥理實(shí)驗(yàn)研究靈苓神的藥理作用。靈苓神能顯著的增加小鼠的入睡個(gè)數(shù)和減少小鼠的活動(dòng)時(shí)間。結(jié)論:靈苓神顆粒劑具有鎮(zhèn)靜安神的作用。

【英文摘要】 To set up preparation technology and quality control methods of Ling-ling Shen Granule and research on its sedative and hypnotic effect by pharmacological experiment.Ling-ling Shen containing the mainly Ganoderma and Poria with hostwood is preparared through using the extrusion method,and studied the pharmacological effect of Ling-ling Shen by the hypnotic experiment and affecting the time of mice's active behaviors experiment.Ling-ling Shen can obviously reduce the active behaviors of mice and increase the number of hypnotic mouse.Ling-ling Shen Granule possesses obviously sedative and hypnotic effect in mice.

【中文關(guān)鍵詞】 靈苓神顆粒劑; 靈芝; 茯神; 鎮(zhèn)靜藥和催眠藥; 小鼠; 苯巴比妥鈉
【英文關(guān)鍵詞】 Ling-ling Shen Granule; Ganoderma lucidum(Curtis:Fr.) Karst.; Poria with hostwood; Hypnotics and sedatives; Mice; Phenobarbital sodium

【文獻(xiàn)出處】 中國(guó)食用菌,Edible Fungi of China,編輯部郵箱,2007年05期 【DOI】CNKI:SUN:ZSYJ.0.2007-05-014